PSSD UK / PSSD Network Meeting with MHRA

Volunteers from PSSD UK and PSSD Network met with MHRA on 5 March 2025 to discuss possible changes to information about irreversible sexual dysfunction within the patient information leaflets for antidepressants in the UK. This is part of the Antidepressant Risk Minimisation Expert Working Group. We submitted this document to the working group and made it clear that we feel that the current information is grossly insufficient and must be amended. A further meeting with MHRA is being discussed, and we will keep the community updated.

It is VERY important that everyone with PSSD completes a yellow card report to MHRA. You can do this as often as you want. It would be worth submitting a new one every 6 months to a year. It is very important that the MedDRA code 10086208 is included, that the report is categorised as ‘Post SSRI Sexual Dysfunction’, and that ‘reduced genital sensation’ is listed as a symptom. There is guidance on submitting the report here: https://www.pssd-uk.org/report-your-experience