Medical Literature

2024

Frequency of self-reported persistent post-treatment genital hypoesthesia among past antidepressant users: a cross-sectional survey of sexual and gender minority youth in Canada and the US - Yassie Pirani, J. Andrés Delgado-Ron, Pedro Marinho, Amit Gupta, Emily Grey, Sarah Watt, Kinnon R. MacKinnon, Travis Salway

Post-SSRI sexual dysfunction: barriers to quantifying incidence and prevalence - David Healy, Dee Mangin

Sexual Dysfunction Induced by Antidepressants - Rene Zeiss, Kathrin Malejko, Bernhard Connemann, Maximilian Gahr, Verena Durner, Heiko Graf

SSRI-Related Tardy Sexual Dysfunction - Ahmed Naguy, Bibi Alamiri

2023

Post -Finasteride Syndrome and Post-SSRI Sexual Dysfunction: Two clinical conditions apparently distant, but very close - Silvia Giatti, Silvia Divicarro, Lucia Cioffi, Roberto Cosimo Melcangi

A clinical guide to rare male sexual disorders - Murat Gül, Mikkel Fode, Ahmet Urkmez, Paolo Capogrosso, Marco Falcone, Selcuk Sarikaya, Ioannis Sokolakis, Afonso Morgado, Andrey Morozov, Maarten Albersen, Giorgio Ivan Russo, Ege Can Serefoglu

A clinical review of antidepressants, their sexual side-effects, post-SSRI sexual dysfunction, and serotonin syndrome - S Marks

Estimating the risk of irreversible post-SSRI sexual dysfunction (PSSD) due to serotonergic antidepressants - Joseph Ben-Sheetrit, Yehonathan Hermon, Shlomo Birkenfeld, Yehiel Gutman, Antonei B. Csoka, Paz Toren

The pathophysiology of Post SSRI Sexual Dysfunction – Lessons from a case study - Samantha Klaas , Jessica Barbut Siva , Maarten Bak , Mark Govers , Rudy Schreiber

Post-SSRI sexual dysfunction and SSRI induced sexual dysfunction - literature review - Eliasz Panek, Damian Jasłowski, Mateusz Rzeszutko, Przemysław Raczkiewicz, Dominika Panasiuk, Mateusz Skrętowicz, Patrycja Szponarowicz, Bartosz Snopkowski, Tomasz Korzec, Jakub Sosnowski

2022

Post-Selective Serotonin Reuptake Inhibitor Sexual Dysfunctions (PSSD): Clinical Experience with a Multimodal Approach - Yacov Reisman, Tommaso B. Jannini, Emmanuele A. Jannini

PSSD Chapter on Textbook of Rare Sexual Medicine Conditions - Yacov Reisman, James G. Pfaus, Lior Lowenstein

2021

Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin - Healy et al, Int J Risk Saf Med

Post-SSRI Sexual Dysfunction (PSSD): Biological Plausibility, Symptoms, Diagnosis, and Presumed Risk Factors -Liran C. Peleg, David Rabinovitch, Yaakov Lavie, Deya M. Rabbie, Itai Horowitz, Sexual Medicine Reviews

Persistent sexual dysfunction after SSRI withdrawal: a scoping review and presentation of 86 cases from the Netherlands -Katherine Chinchilla Alfaro, Florence van Hunsel & Corine Ekhart, Netherlands Pharmacovigilance Centre Lareb

Characterizing Post-SSRI sexual dysfunction and its impact on quality of life through an international online survey -Alaina Studt et al, The University of Iowa

Effects of paroxetine treatment and its withdrawal on neurosteroidogenesis -Silvia Giatti, Silvia Diviccaro, Lucia Cioffi, Eva Falvo, Donatella Caruso, Roberto C. Melcangi, Psychoneuroendocrinology

2020

Discontinuation emergent symptoms after SSRI and SNRI treatment: a systematic literature review -Celine Lüning, Universität Witten/Herdecke

Post SSRI Sexual Dysfunction (PSSD): Ten Year Retrospective Chart Review (The Journal of Urology) - Ahad Waraich, Channing Clemons, Roma Ramirez, Jessica Yih, Sue Goldstein, Irwin Goldstein.

Antidepressant-induced sexual dysfunction (The Medical Journal of Australia) - Jody Rothmore.

Post SSRI sexual dysfunction (BMJ) - Y. Reisman

Antidepressants and sexual dysfunction: a history (Royal Society of Medicine) - David  Healy

A Paradigmatic Case of Post-selective Serotonin Reuptake Inhibitors Sexual Dysfunction or Withdrawal After Discontinuation of Selective Serotonin Reuptake Inhibitors  (Journal of Clinical Psychopharmacology) - Fiammetta Cosci

2019

Are There Any Sex/Gender Differences in Post-Selective Serotonin Reuptake Inhibitors (SSRI) Sexual Dysfunction (PSDD)? (Current Sexual Health Reports) - Y. Reisman

Post SSRI Sexual Dysfunction: A Bioelectric Mechanism? (Bioelectricity)  - David Healy, Joshua LaPalme and Michael Levin

Clinical judgements, not algorithms, are key to patient safety - an essay (BMJ) - David Healy and Dee Mangin

Post SSRI Sexual Dysfunction and other enduring sexual dysfunctions (Epidemiology and Psychiatric Sciences) - David Healy

Persistent adverse effects of antidepressants (Epidemiology and Psychiatric Sciences) - Joanna Moncrieff

Post-SSRI sexual dysfunction: Patient experiences of engagement with healthcare professionals (International Journal of Risk and Safety in Medicine) - David Healy, J Le Noury, Dee Mangin

Towards improving post SSRI sexual dysfunction by using nutriceuticals: Lessons from a case study (Journal of Sex and Marital Therapy) - Rocco Salvatore Calabro, Rosaria De Luca, Alfredo Manuli, Simona Portaro, Antonino Naro, Fabrizio Quattrini

2018

The Effect of Citalopram on Genome-Wide DNA Methylation of Human Cells (International Journal of Genomics) - Riya Kanherkar, Bruk Getachew, Joseph Ben-Sheetrit, Sudhir Varma, Thomas Heinbockel, Yousef Tizabi, Antonei Csoka

Citizen petition: Sexual side effects of SSRIs and SNRIs (International Journal of Risk and Safety in Medicine) - David Healy

Enduring sexual dysfunction after treatment with antidepressants, 5a-reductase inhibitors and isotretinoin: 300 cases (International Journal of Risk and Safety in Medicine) - David Healy, Joanna Le Noury, Derelie Mangin

Post Finasteride syndrome and post SSRI sexual dysfunction: two sides of the same coin? (Endocrine) - S Giatti, S Diviccaro, G Panzica, R Melcangi

Post SSRI Sexual Dysfunction: Preclinical to Clinical. Is It Fact or Fiction? (Sexual Medicine Reviews) - Enis Rauf Coskuner, Mehmet Gokhan Culha, Burak Ozkan, Elcin Orhan Kaleagasi

2017

Post-SSRI Sexual Dysfunction: A Literature Review (Sexual Medicine Reviews) - A Bala, HMT Nguyen, WJD Hellstrom

Post Serotonin Selective Re-uptake Inhibitors Persistent Sexual Dysfunction after Serotonin Selective Re-uptake Inhibitors Treatment: A Case Report after Stopping Paroxetine  Rodriguez et al.

Sexual Consequences of Post SSRI Syndrome (International Society for Sexual Medicine) - Y Reisman

2016

Persistent sexual dysfunction after early exposure to SSRIs: Systematic review of animal studies (The International Journal of risk and safety in medicine)  - AL Simonsen, PB Danborg, PC Gøtzsche

2015

Post SSRI Sexual Dysfunction: Clinical Characterization and Preliminary Assessment of Contributory Factors and Dose-Response Relationship  (Journal of Clinical Psychopharmacology) - J Ben-Sheetrit, D Aizenberg, AB Csoka, A Weizman, H Hermesh

2014

Penile anesthesia in post SSRI sexual dysfunction (PSSD) responds to low-power laser irradiation: A case study and hypothesis about the role of transient receptor potential (TRP) ion channels (European Journal of Pharmacology) - MD Waldinger, RS Van Coevorden, DH Schweitzer, J Georgiadis 

One hundred and twenty cases of enduring sexual dysfunction following treatment (International Journal of Risk and Medicine) - C Hogan, J Le Noury, D Healy, D Mangin 

Does sexual dysfunction persist upon discontinuation of selective serotinin reuptake inhibitors? - G.C Ekhart, E.P Van Puijenbroek

2009

Persistent sexual dysfunction in genitouinary medicine clinicattendees induced by selective serotonin reuptake inhibitors (International Journal of STDs and Aids) - KD Farnsworth, WW Dinsmore

2008

Persistent Genital Arousal Disorder in Women: Case Reports of Association with Anti-Depressant Usage and Withdrawal (Journal of Sex and Marital Therapy) - SR Leiblum, D Goldmeier

Sexual Side Effects of Antidepressant Medications: An Informed Consent Accountability Gap (Journal of Contemporary Psychotherapy) - AS Bahrick, M Harris

Persistence of Sexual Dysfunction Side Effects After Discontinuation of Antidepressant Medications: Emerging Evidence  (The Open Psychology Journal) - AS Bahrick

Persistent Sexual Dysfunction after Discontinuation of Selective Serotonin Re-uptake Inhibitors (The Journal of Sexual Medicine) - AB Csoka, A Bahrick, OP Mehtonen

2007

Prolonged Post-Treatment Genital Anesthesia and Sexual Dysfunction Following Discontinuation of Citalopram and the Atypical Antidepressant Nefazodone (The Open Women's Health Journal) - R Kauffman, A Murdock

2006

Post SSRI Sexual Dysfunction - A Bahrick

Persistent Sexual Side Effects after SSRI Discontinuation (Psychotherapy and Psychosomatics) - A Csoka, S Shipko

Genital anaesthesia persisting six years after setraline discontinuation (Journal of Sex and Marital Therapy) - JM Bolton, J Sareen